Below is a list of the top 300 blockchain companies in the US

CompanyCityStateCruncbase Rank
CoinbaseSan Francisco California5
RippleSan Francisco California83
RobinhoodPalo Alto California100
CoinTrackerSan Francisco California182
ChainalysisNew York New York184
HarborSan Francisco California217
TezosSan Francisco California627
LibraTaxSan Francisco California819
UpholdSan Francisco California1015
CoinListSan Francisco California1108
Origin ProtocolSan Francisco California1285
Chia NetworkSan Francisco California1537
ChronicledSan Francisco California1548
OB1Centreville Virginia1674
ObENPasadena California1696
Celsius NetworkNew York New York1741
GemVenice California1797
Rare BitsSan Francisco California1807
Storj LabsAtlanta Georgia2237
CakeCodesSeattle Washington2353
TenfoldAustin Texas2397
tZeroNew York New York2591
SensayVenice California3091
NuCypherSan Francisco California3474
LedgerXNew York New York3786
AirfoxBoston Massachusetts3855
Kraken Bitcoin ExchangeSan Francisco California4036
Hedera HashgraphDallas Texas4037
SymbiontNew York New York4126
Flipside CryptoBoston Massachusetts4402
EveripediaLos Angeles California4407
FilamentReno Nevada4479
CryptoMoveOakland California4602
BasisHoboken New Jersey4732
SnapcardSan Francisco California4969
carbon-12-labsNew York New York5285
LinoCupertino California5390
SinglePointPhoenix Arizona5678
CoinDeskNew York New York5928
TOK.tvSan Francisco California6149
TradeBlockNew York New York6219
AugmateNew York New York6221
Bitwise Asset ManagementSan Francisco California6431
VoatzBoston Massachusetts6451
1World OnlinePalo Alto California6780
BitClaveMountain View California7565
CrowdzSunnyvale California7583
AlphaPointNew York New York7841
WemarkSan Francisco California8015
Bitnet TechnologiesSan Francisco California8161
YoursSan Francisco California8619
Shift PaymentsSan Francisco California8620
DbrainDelaware City Delaware8689
PurseSan Francisco California9294
CircleBoston Massachusetts9580
chiliZMalta Illinois9735
BitBounceRedwood City California9781
HijroLexington Kentucky10237
Radar RelayFort Collins Colorado10260
BodhiSan Francisco California10958
BoardwalktechPalo Alto California11096
Swarm FundPalo Alto California11816
ZEROCOIN ELECTRIC COIN COMPANYDenver Colorado11903
Lucid SightLos Angeles California11938
GiveDirectlyNew York New York12076
HedgySan Francisco California12977
Quantstamp TechnologiesSan Francisco California13464
SureRemitSan Francisco California13606
UnikoinGoldSeattle Washington13800
aXpireNew York New York14677
StamperySan Mateo California14954
NuIDSan Francisco California15559
VIASomerville Massachusetts16601
Commonwealth CryptoBoston Massachusetts16895
BitWallet™Houston Texas16968
CoinmeSeattle Washington17093
SyncFabSan Leandro California17203
SatochiNew York New York18063
QulsarSan Jose California18710
SpigaBoulder Colorado19501
UPGRADEDWalnut Creek California20070
GluonLivermore California20456
BenSan Diego California20921
RealBlocksNew York New York21488
Subdream StudiosLos Altos California21871
VeradyAtlanta Georgia21935
DominodeBoca Raton Florida22202
BuroHQNew York New York22889
Data Gumbo CorporationHouston Texas23518
MegaHootSpring Hill Florida23536
SharkPaySanta Clara California23583
InXeroAustin Texas24332
UBBYSan Francisco California24554
BitCADWalnut California24694
OneiroBoston Massachusetts25190
BitTellerAustin Texas25731
Multicoin CapitalAustin Texas25831
CryptykSan Francisco California26923
BIGcontrolsSausalito California27100
HexelSan Francisco California27550
SmartAxiomFullerton California27815
DeepRadiologySanta Monica California28330
GeminiNew York New York29079
OpenSeaSan Francisco California29206
APPCityLife®Albuquerque New Mexico29505
UniCoin Blockchain Inc.San Diego California29765
EpiphyteSan Francisco California29864
Omega GridChicago Illinois30316
Solar Site DesignNashville Tennessee30324
SericaSan Francisco California31954
AssetXOrlando Florida33101
SoteSan Francisco California33367
SkuchainMountain View California34574
Workday VenturesSan Francisco California35225
CarSnatchSan Francisco California35504
Momo Networks (MOMO Board)San Francisco California35834
PoloniexWilmington Delaware36124
MyEtherWalletLos Angeles California36152
WeTuringSanta Clara California37502
TheMonetizrAtlanta Georgia40561
Blockchain Technologies CorpNew York New York41433
SimplyVital HealthWatertown Massachusetts41926
OmniexSan Francisco California42746
MyStreamNew York New York43654
TigerEx - Smart ETFs for CryptocurrenciesSunnyvale California44720
TasheLos Angeles California45628
OpenAVNNew York New York45852
The Picks & Shovels Co.San Francisco California46016
XYO NetworkSan Diego California46493
Tangible CryptographyWilmington Delaware49555
Everythink IncSan Francisco California51129
Parachute8 Inc.Salida Colorado51196
CoinmoAtlanta Georgia52128
Gamer AmmoBattle Creek Michigan52479
EmpowerSan Francisco California54672
BloqChicago Illinois54909
Bittrex LLCLas Vegas Nevada55122
BR?VO Tip or PayPhoenix Arizona55575
RepublicNew York New York55994
DogetipbotArcata California56083
dYdXSan Francisco California57337
TrustTokenSan Francisco California57733
New ContextSan Francisco California58756
SafeChain Inc.Columbus Ohio60215
T45 Investments Inc.Alexandria Virginia62413
WorldLinkFrisco Texas63544
Nebula GenomicsBoston Massachusetts64188
Crypto.IQSarasota Florida65891
HydrogenNew York New York66309
Tally CapitalChicago Illinois66478
SmartyAdsNew York New York66579
Cipher BrowserSan Francisco California66643
SweetbridgePhoenix Arizona67010
Funding WonderMiami Florida67897
Constellation LabsSan Francisco California67998
Strategic CoinNew York New York73219
ArcTouchSan Francisco California75218
Dispatch LabsSan Francisco California75461
One Car PaymentEaston Pennsylvania76505
Blockweather HoldingsDover Delaware76767
OxynJersey City New Jersey76994
CryptowerkRedwood City California77776
Bitcoin IRASherman Oaks California78384
PopChestSanta Monica California78921
TernioNew York New York80283
FlexaNew York New York80962
Microhash IncNew York New York81142
ZenCashCumming Georgia82185
KezaNew York New York82610
Verge CurrencyFort Myers Florida83520
TrustLogicsAtlanta Georgia85412
TronSan Francisco California86395
Nebel.TVMountain View California86525
Money20/20New York New York87130
CumberlandChicago Illinois87162
ProvectusPalo Alto California87313
JumptuitNew York New York88793
Look AppStanford California88844
RefereumSan Francisco California89331
Open PlatformSan Francisco California90200
Tides - Decentralized insuranceSan Francisco California90385
EverMarketsSan Francisco California90804
CoinifySioux City Iowa90857
Thunder TokenSunnyvale California91119
EnblocColumbus Ohio92090
Emerging InsiderChicago Illinois93445
TurbadiumSan Francisco California93457
MootiNew York New York94358
Synapse AISan Francisco California94362
Global Digital Asset ExchangeSan Francisco California96825
SolidXNew York New York97932
LDGR Capital ManagementDenver Colorado98253
PrivacyShell CorpSan Francisco California98390
EvercoinSanta Clara California98699
CardstackNew York New York99435
Science2successDes Moines Iowa99851
BitbutterSan Francisco California100593
AtonomiSeattle Washington100633
FLATLAYLos Angeles California101181
Node CapitalNew York New York101965
ICO AlertPittsburgh Pennsylvania103032
CryptoParencySan Francisco California103947
MintHealthSan Diego California105428
EthVenturesChicago Illinois110526
Digital Currency CouncilNew York New York110842
NexusScottsdale Arizona112234
TokenZooChicago Illinois112876
SolidifiedBoston Massachusetts114295
UbiNET Inc.St. Petersburg Florida115530
BNFT - Blockchain BenefitsVenice California116247
AEDAN IncSan Francisco California116978
OckamSan Francisco California118199
Connected FintechNew York New York118423
TremorGreenwich Connecticut119624
DjinnFizz Inc (BandDjinni)San Francisco California121059
Ideas By NatureDenver Colorado122117
BlockstateSan Francisco California122308
AusumSan Francisco California123476
MIMIR Blockchain SolutionsAtlanta Georgia124992
NextPakkMinneapolis Minnesota125792
Preloaded WalletsSan Francisco California125935
NeuryxProvo Utah127438
WampeiCentennial Colorado127901
Launch PopLos Angeles California128071
SolanaSan Francisco California128373
BIGDATAGUYSWashington District of Columbia129963
DoubleNova GroupSan Francisco California130453
ZillionLos Altos California130688
CointaxesNew York New York132274
I/O DigitalMiami Florida133808
yBitcoinHuntsville Alabama134785
Blockchain HealthSan Francisco California135436
VoltmarketsHouston Texas135637
Williams Technology GroupAustin Texas138140
The LendingCoinBoise Idaho138765
Finesis LLCLewes Delaware139304
Duality Blockchain SolutionsSan Antonio Texas141068
BitBayMiami Florida142788
CryptonexScotland Indiana142881
ZS BlockchainSan Francisco California143512
XcelchainSan Francisco California146115
REcoinLas Vegas Nevada146450
WaveAccessLas Vegas Nevada147910
SeaficoNew York New York152343
CryptoBridgeStuart Florida157072
PriogenNetherlands Missouri157608
MetaSquare IncNew York New York157662
BestcoinsSunnyvale California158389
Felix HomesNew York New York159351
IotexMenlo Park California160515
Purple OrangeChicago Illinois163264
Validareum Inc.New York New York164406
CBlocksMiami Florida166822
Atoma TechnologiesAnn Arbor Michigan167123
HTMLcoinChicago Illinois167270
PointNurseNashville Tennessee167396
Crypto AnswersWillow Grove Pennsylvania168256
DecredChicago Illinois169411
SpankChainVenice California171345
Azran FinancialLos Angeles California174119
Geopay.meClearwater Florida175405
SynctricsPalo Alto California177018
Pactum IOAustin Texas178452
Standard American MiningRaleigh North Carolina183777
1Kosmos - BlockIDHoboken New Jersey187512
SoundprufMinneapolis Minnesota187894
Transonic TransportationMandeville Louisiana188383
Quantum Medical TransportSugar Land Texas188923
Benjamin Capital Management Group Inc.New York New York189119
BleexyChantilly Virginia189179
ChainBytesAllentown Pennsylvania190729
Global Blockchain Business CouncilWashington District of Columbia193179
ConfidealIreland Indiana198030
Amalgamated EnterprisesBoston Massachusetts201998
VRBexHouston Texas206562
VeritaseumNew York New York207239
JITLAPhoenix Arizona208489
Ong.socialKirkland Washington209948
Creative Investment ResearchWashington District of Columbia211958
Crypto CriticsTempe Arizona218071
Crypto CoinsureChicago Illinois230852
Bitcoin D.A.V.E.New York New York231297
VettyNew York New York233567
Blackridge SoftwareOrem Utah239802
Amulet PlatformSan Jose California242851
VertaloAustin Texas249010
Dagcoin CryptocurrencyBensenville Illinois249435
DatamarxNew York New York250600
7QUBESChicago Illinois269659
ATB CoinNew York New York274173
ModeneroAtlanta Georgia294342
MentatNew York New York303985
TunnelBoston Massachusetts311690
ZettabytesSan Jose California314654
SwapchainScottsdale Arizona319901
Guppy GroupFairfax Virginia326106
SuploadLas Vegas Nevada336019
BisonNew York New York337744
MOURI TechDallas Texas369722

Source: Crunchbase

Heatmap of top 300 blockchain companies in US